Què fem:
Publicacions científiques

Total publicacions.: 3

Total publicacions.: 1

Total publicacions.: 2

Total publicacions.: 8

Total publicacions.: 9

Total publicacions.: 6

Total publicacions.: 6

Total publicacions.: 6

Factor d'impacte total: 25,39

Total publicacions.: 9

Factor d'impacte total: 30,13

Total publicacions.: 11

Factor d'impacte total: 51,64

Total publicacions.: 11

Factor d'impacte total: 67,03

Total publicacions.: 9

Factor d'impacte total: 42,93

Total publicacions.: 15

Factor d'impacte total: 51,54

F.I.: 3.92
Sembragiline in Moderate Alzheimer’s Disease:
Results of a Randomized, Double-Blind, Placebo-Controlled Phase II Trial (MAyflOwer RoAD). Nave S, Doody RS, Boada M, Grimmer T, Savola JM, Delmar P, Pauly-Evers M, Nikolcheva T, Czech C, Borroni E, Ricci B, Dukart J, Mannino M, Carey T, Moran E, Gilaberte I, Muelhardt NM, Gerlach I, Santarelli L, Ostrowitzki S, Fontoura P. J Alzheimers Dis. 2017 May 26.. [Epub ahead of print]

Total publicacions.: 19

Factor d'impacte total: 118,89

F.I.: 3.92
Social Representation of Dementia: An Analysis of 5,792 consecutive Cases Evaluated in a Memory Clinic.
Cañabate P, Martínez G, Rosende-Roca M, Moreno M, Preckler S, Valero S, Sotolongo O, Hernández I, Alegret M, Ortega G, Espinosa A, Mauleón A, Vargas L, Rodríguez O, Abdelnour C, Sánchez D, Martín E, Ruiz A, Tárraga L, Boada M. J Alzheimers Dis. 2017 May 17. [Epub ahead of print]

Total publicacions.: 25

Factor d'impacte total: 127,5

Total publicacions.: 19

Factor d'impacte total: 135.03

Total publicacions.: 13

Factor d'impacte total: 79.26

Total publicacions.: 20

Factor d'impacte total: 133.82

Alzheimers Dement. 2018 May;14(5):634-643. F. I.: 9.478. doi: 10.1016/j.jalz.2017.10.005. Epub 2017 Nov 20.
Exploring APOE genotype effects on AD risk and beta-amyloid burden in individuals with subjective cognitive decline: the FACEHBI study baseline results.
Sonia Moreno –Grau, O. Rodríguez-Gomez, A. Sanabria, A. Perez-Cordon, D. Sánchez-Ruiz, C. Abdelnour, S. Valero, I. Hernández, M. Rosende-Roca, A. Mauleón, L. Vargas, A. Lafuente, S. Gil, M. A. Santos-Santos, M. Alegret, A. Espinosa, G. Ortega, M. Guitart, A. Gailhajanet, I. de Rojas, O. Sotolongo-Grau, S. Ruiz, N. Aguilera, J. Papasey, E. Martín, E. Peleja, Alzheimer’s Disease Neuroimaging Initiative*, F. Lomeña, F. Campos, A. Vivas, M.Gomez-Chiari, M.A. Tejero, J. Giménez, M. Serrano-Ríos, A. Orellana, L. Tárraga, A. Ruiz, M.Boada, on behalf of the FACEHBI study group.
Curr Alzheimer Res. 2018;15(6):511-530. F. I.: 2.952. doi: 10.2174/1567205014666170725130819. Epub 2017 Jul 25.
Frontotemporal Lobar Degeneration. Review and update for clinical neurologists.
Hernández I, Fernández MV, Tàrraga L, Boada M, Ruiz A.
Mol Psychiatry. 2018 Apr;23(4):963-972. F.I.: 13.204. doi: 10.1038/mp.2017.81. Epub 2017 May 2.
Genetic risk for schizophrenia and psychosis in Alzheimer disease.
DeMichele-Sweet MAA, Weamer EA, Klei L, Vrana DT, Hollingshead DJ, Seltman HJ, Sims R, Foroud T, Hernandez I, Moreno-Grau S, Tárraga L, Boada M, Ruiz A, Williams J, Mayeux R, Lopez OL, Sibille EL, Kamboh MI, Devlin B, Sweet RA.
Alzheimers Res Ther. 2017 Dec 8;9(1):95. F.I.: 6.154. doi: 10.1186/s13195-017-0318-y.
A phase III randomized trial of gantenerumab in prodromal Alzheimer's disease.
Ostrowitzki S, Lasser RA, Dorflinger E, Scheltens P, Barkhof F, Nikolcheva T, Ashford E, Retout S, Hofmann C, Delmar P, Klein G, Andjelkovic M, Dubois B, Boada M, Blennow K, Santarelli L, Fontoura P; SCarlet RoAD Investigators.
Diabetes. 2017 Dec;66(12):3098-3104. F. I.: 8.684. doi: 10.2337/db17-0382. Epub 2017 Sep 26.
Retinal Microperimetry: A New Tool for Identifying Type 2 Diabetic Patients at Risk of Developing Alzheimer´s Disease.
Ciudin A, Simó-Servat O, Hernández C, Arcos G, Diego S, Sanabria Á, Sotolongo Ó, Hernández I, Boada M, Simó R.
Cochrane Database Syst Rev. 2017 Nov 22;11:CD012883. F.I.: 6.12. doi: 10.1002/14651858.CD012883.
18F PET with florbetaben for the early diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI).
Martínez G, Vernooij RW, Fuentes Padilla P, Zamora J, Flicker L, Bonfill Cosp X.
Cochrane Database Syst Rev. 2017 Nov 22;11:CD012884. F.I.: 6.12. doi: 10.1002/14651858.CD012884.
18F PET with flutemetamol for the early diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI).
Martínez G, Vernooij RW, Fuentes Padilla P, Zamora J, Flicker L, Bonfill Cosp X.
Cochrane Database Syst Rev. 2017 Nov 22;11:CD012216. F.I.: 6.12. doi: 10.1002/14651858.CD012216.pub2.
18F PET with florbetapir for the early diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI).
Martínez G, Vernooij RW, Fuentes Padilla P, Zamora J, Bonfill Cosp X, Flicker L.
JAMA Neurol. 2017 Oct 1;74(10):1178-1189. F. I.: 10.03. doi: 10.1001/jamaneurol.2017.2188.
Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease: A Meta-analysis.
Neu SC, Pa J, Kukull W, Beekly D, Kuzma A, Gangadharan P, Wang LS, Romero K, Arneric SP, Redolfi A, Orlandi D, Frisoni GB, Au R, Devine S, Auerbach S, Espinosa A, Boada M, Ruiz A, Johnson SC, Koscik R, Wang JJ, Hsu WC, Chen Y, Toga AW.
J Prev Alz Dis 2016;3(2):68-74. doi: 10.14283/jpad.2016.97.
Registries and Cohorts to Accelerate Early Phase Alzheimer’s Trials. A Report from the E.U./U.S. Clinical Trials in Alzheimer’s Disease Task Force.
P. Aisen, J. Touchon, S. Andrieu, M. Boada, R. Doody, R.L. Nosheny, J.B. Langbaum, L. Schneider, S. Hendrix, G. Wilcock, J.L. Molinuevo, C. Ritchie, P.-J. Ousset, J. Cummings, R. Sperling, S.T. DeKosky, S. Lovestone, H. Hampel, R. Petersen, V. Legrand, M. Egan, C. Randolph, S. Salloway, M. Weiner, B. Vellas, and Task Force Members.
Physica A. 2017 Apr 15;472:86-93. doi:10.1016/j.physa.2016.12.086. Epub 2017 Jan 4.
A physical model for dementia.
O. Sotolongo-Costa, L.M. Gaggero-Sager, J.T. Becker, F. Maestuf, O. Sotolongo-Grau, for the Alzheimer’s Disease Neuroimaging Initiative.
Alzheimers Dement. 2017 Sep;13(9):1013-1023. I.F.: 11,619. doi: 10.1016/j.jalz.2017.01.019. Epub 2017 Mar 3
The impact of automated hippocampal volumetry on diagnostic confidence in patients with suspected Alzheimer's disease: An EADC study.
Bosco P, Redolfi A, Bocchetta M, Ferrari C, Mega A, Galluzzi S, Austin M, Chincarini A, Collins DL, Duchesne S, Maréchal B, Roche A, Sensi F, Wolz R, Alegret M, Assal F, Balasa M, Bastin C, Bougea A, Emek-Savaş DD, Engelborghs S, Grimmer T, Grosu G, Kramberger MG, Lawlor B, Mandic Stojmenovic G, Marinescu M, Mecocci P, Molinuevo JL, Morais R, Niemantsverdriet E, Nobili F, Ntovas K, O'Dwyer S, Paraskevas GP, Pelini L, Picco A, Salmon E, Santana I, Sotolongo-Grau O, Spiru L, Stefanova E, Popovic KS, Tsolaki M, Yener GG, Zekry D, Frisoni GB.
Nat Genet. 2017 Sep;49(9):1373-1384. F.I.: 27.959 (2 years). doi: 10.1038/ng.3916. Epub 2017 Jul 17.
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P, Grove ML, Vardarajan BN, Hiltunen M, Nöthen MM, White CC, Hamilton-Nelson KL, Epelbaum J, Maier W, Choi SH, Beecham GW, Dulary C, Herms S, Smith AV, Funk CC, Derbois C, Forstner AJ, Ahmad S, Li H, Bacq D, Harold D, Satizabal CL, Valladares O, Squassina A, Thomas R, Brody JA, Qu L, Sánchez-Juan P, Morgan T, Wolters FJ, Zhao Y, Garcia FS, Denning N, Fornage M, Malamon J, Naranjo MCD, Majounie E, Mosley TH, Dombroski B, Wallon D, Lupton MK, Dupuis J, Whitehead P, Fratiglioni L, Medway C, Jian X, Mukherjee S, Keller L, Brown K, Lin H, Cantwell LB, Panza F, McGuinness B, Moreno-Grau S, Burgess JD, Solfrizzi V, Proitsi P, Adams HH, Allen M, Seripa D, Pastor P, Cupples LA, Price ND, Hannequin D, Frank-García A, Levy D, Chakrabarty P, Caffarra P, Giegling I, Beiser AS, Giedraitis V, Hampel H, Garcia ME, Wang X, Lannfelt L, Mecocci P, Eiriksdottir G, Crane PK, Pasquier F, Boccardi V, Henández I, Barber RC, Scherer M, Tarraga L, Adams PM, Leber M, Chen Y, Albert MS, Riedel-Heller S, Emilsson V, Beekly D, Braae A, Schmidt R, Blacker D, Masullo C, Schmidt H, Doody RS, Spalletta G, Jr WTL, Fairchild TJ, Bossù P, Lopez OL, Frosch MP, Sacchinelli E, Ghetti B, Yang Q, Huebinger RM, Jessen F, Li S, Kamboh MI, Morris J, Sotolongo-Grau O, Katz MJ, Corcoran C, Dunstan M, Braddel A, Thomas C, Meggy A, Marshall R, Gerrish A, Chapman J, Aguilar M, Taylor S, Hill M, Fairén MD, Hodges A, Vellas B, Soininen H, Kloszewska I, Daniilidou M, Uphill J, Patel Y, Hughes JT, Lord J, Turton J, Hartmann AM, Cecchetti R, Fenoglio C, Serpente M, Arcaro M, Caltagirone C, Orfei MD, Ciaramella A, Pichler S, Mayhaus M, Gu W, Lleó A, Fortea J, Blesa R, Barber IS, Brookes K, Cupidi C, Maletta RG, Carrell D, Sorbi S, Moebus S, Urbano M, Pilotto A, Kornhuber J, Bosco P, Todd S, Craig D, Johnston J, Gill M, Lawlor B, Lynch A, Fox NC, Hardy J; ARUK Consortium, Albin RL, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Baldwin CT, Barnes LL, Barral S, Beach TG, Becker JT, Bigio EH, Bird TD, Boeve BF, Bowen JD, Boxer A, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Carroll SL, Diaz CC, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, Dick M, Duara R, Evans DA, Faber KM, Fallon KB, Fardo DW, Farlow MR, Ferris S, Foroud TM, Galasko DR, Gearing M, Geschwind DH, Gilbert JR, Graff-Radford NR, Green RC, Growdon JH, Hamilton RL, Harrell LE, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Abner E, Jin LW, Jun G, Karydas A, Kaye JA, Kim R, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lunetta KL, Lyketsos CG, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Morris JC, Murrell JR, Myers AJ, O'Bryant S, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Perry W, Peskind E, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosen HJ, Rosenberg RN, Sager MA, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Garzia F, Golamaully F, Septier G, Engelborghs S, Vandenberghe R, De Deyn PP, Fernadez CM, Benito YA, Thonberg H, Forsell C, Lilius L, Kinhult-Stählbom A, Kilander L, Brundin R, Concari L, Helisalmi S, Koivisto AM2, Haapasalo A, Dermecourt V, Fievet N, Hanon O, Dufouil C, Brice A, Ritchie K, Dubois B, Himali JJ, Keene CD, Tschanz J, Fitzpatrick AL, Kukull WA, Norton M, Aspelund T, Larson EB, Munger R, Rotter JI, Lipton RB, Bullido M, Hofman A, Montine TJ, Coto E, Boerwinkle E, Petersen RC, Alvarez V, Rivadeneira F, Reiman EM, Gallo M, O'Donnell C, Reisch JS, Bruni AC, Royall DR, Dichgans M, Sano M, Galimberti D, St George-Hyslop P, Scarpini E, Tsuang DW, Mancuso M, Bonuccelli U, Winslow AR, Daniele A, Wu CK; GERAD/PERADES, CHARGE, ADGC, EADI, Peters O, Nacmias B, Riemenschneider M, Heun R, Brayne C, Rubinsztein DC, Bras J, Guerreiro R, Al-Chalabi A, Shaw CE, Collinge J, Mann D, Tsolaki M, Clarimón J, Sussams R, Lovestone S, O'Donovan MC, Owen MJ, Behrens TW, Mead S, Goate AM, Uitterlinden AG, Holmes C1, Cruchaga C, Ingelsson M, Bennett DA, Powell J, Golde TE, Graff C, De Jager PL, Morgan K, Ertekin-Taner N, Combarros O, Psaty BM, Passmore P, Younkin SG, Berr C, Gudnason V, Rujescu D, Dickson DW, Dartigues JF, DeStefano AL, Ortega-Cubero S, Hakonarson H, Campion D, Boada M, Kauwe JK, Farrer LA, Van Broeckhoven C, Ikram MA, Jones L, Haines JL, Tzourio C, Launer LJ, Escott-Price V, Mayeux R, Deleuze JF, Amin N, Holmans PA, Pericak-Vance MA, Amouyel P, van Duijn CM, Ramirez A, Wang LS, Lambert JC, Seshadri S, Williams J, Schellenberg GD.
J Prim Prev. 2017 Aug;38(4):345-362. I.F.: 1,33. doi: 10.1007/s10935-017-0466-7.
Mapping the Health Information Landscape in a Rural, Culturally Diverse Region: Implications for Interventions to Reduce Information Inequality.
Ramírez AS, Estrada E, Ruiz A.
J Diabetes Complications. 2017 Aug;31(8):1272-1274. F.I.: 2.73. doi: 10.1016/j.jdiacomp.2017.04.018. Epub 2017 Apr 19.
Type 2 diabetes is an independent risk factor for dementia conversion in patients with mild cognitive impairment.
Ciudin A, Espinosa A, Simó-Servat O, Ruiz A, Alegret M, Hernández C, Boada M, Simó R.
J Alzheimers Dis. 2017;58(4):1217-1228. F.I.: 3.731. doi: 10.3233/JAD-161309.
Sembragiline in Moderate Alzheimer's Disease: Results of a Randomized, Double-Blind, Placebo-Controlled Phase II Trial (MAyflOwer RoAD).
Nave S, Doody RS, Boada M, Grimmer T, Savola JM, Delmar P, Pauly-Evers M, Nikolcheva T, Czech C, Borroni E, Ricci B, Dukart J, Mannino M, Carey T, Moran E, Gilaberte I, Muelhardt NM, Gerlach I, Santarelli L, Ostrowitzki S, Fontoura P.
Front Neurol. 2017 Jun 1;8:228. F.I.: 6.4. doi: 10.3389/fneur.2017.00228. eCollection 2017.
Challenges for Service Robots-Requirements of Elderly Adults with Cognitive Impairments.
Korchut A, Szklener S, Abdelnour C, Tantinya N, Hernández-Farigola J, Ribes JC, Skrobas U, Grabowska-Aleksandrowicz K, Szczęśniak-Stańczyk D, Rejdak K.
J Alzheimers Dis. 2017;58(4):1099-1108. F.I.: 3.731. doi: 10.3233/JAD-161119.
Social Representation of Dementia: An Analysis of 5,792 Consecutive Cases Evaluated in a Memory Clinic.
Cañabate P, Martínez G, Rosende-Roca M, Moreno M, Preckler S, Valero S, Sotolongo O, Hernández I, Alegret M, Ortega G, Espinosa A, Mauleón A, Vargas L, Rodríguez O, Abdelnour C, Sánchez D, Martín E, Ruiz A, Tárraga L, Boada M.
J Alzheimers Dis. 2017;57(2):447-459. F.I.: 3.731. doi: 10.3233/JAD-161223.
Cognitive Composites Domain Scores Related to Neuroimaging Biomarkers within Probable-Amnestic Mild Cognitive Impairment-Storage Subtype.
Espinosa A, Alegret M, Pesini P, Valero S, Lafuente A, Buendía M, San José I, Ibarria M, Tejero MA, Giménez J, Ruiz S, Hernández I, Pujadas F, Martínez-Lage P, Munuera J, Arbizu J, Tárraga L, Hendrix SB, Ruiz A, Becker JT, Landau SM, Sotolongo-Grau O, Sarasa M, Boada M.
J Alzheimers Dis. 2017;57(2):625-632. F.I.: 3.731. doi: 10.3233/JAD-160915.
Impact of Recruitment Methods in Subjective Cognitive Decline.
Abdelnour C, Rodríguez-Gómez O, Alegret M, Valero S, Moreno-Grau S, Sanabria Á, Hernández I, Rosende-Roca M, Vargas L, Mauleón A, Sánchez D, Espinosa A, Ortega G, Pérez-Cordón A, Diego S, Gailhajanet A, Guitart M, Sotolongo-Grau Ó, Ruiz A, Tárraga L, Boada M.

Total publicacions.: 30

Factor d'impacte total: 211,45

Alzheimers Dement. 2018 Dec 13. pii: S1552-5260(18)33563-5. F.I. 12,74 doi: 10.1016/j.jalz.2018.10.003
Subjective cognitive decline and rates of incident Alzheimer's disease and non-Alzheimer's disease dementia.
Slot RER1, Sikkes SAM2, Berkhof J3, Brodaty H4, Buckley R5, Cavedo E6, Dardiotis E7, Guillo-Benarous F8, Hampel H6, Kochan NA9, Lista S6, Luck T10, Maruff P11, Molinuevo JL12, Kornhuber J13, Reisberg B8, Riedel-Heller SG14, Risacher SL15, Roehr S16, Sachdev PS9, Scarmeas N17, Scheltens P1, Shulman MB8, Saykin AJ15, Verfaillie SCJ1, Visser PJ18, Vos SJB19, Wagner M20, Wolfsgruber S20, Jessen F21; Alzheimer's Disease Neuroimaging Initiative, the DESCRIPA working group, the INSIGHT-preAD study group, on behalf of the SCD-I working group, van der Flier WM22.
Nat Med. 2018 Dec 3. F.I. 32,62 doi: 10.1038/s41591-018-0223-3
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia.
Swarup V1, Hinz FI1, Rexach JE1, Noguchi KI2, Toyoshiba H2, Oda A2, Hirai K2, Sarkar A1, Seyfried NT3,4, Cheng C5, Haggarty SJ5; International Frontotemporal Dementia Genomics Consortium, Grossman M6, Van Deerlin VM7, Trojanowski JQ7, Lah JJ4, Levey AI4, Kondou S2, Geschwind DH8,9,10.
Alzheimers Res Ther. 2018 Nov 29;10(1):119. F.I. 5.015 doi: 10.1186/s13195-018-0444-1
Correlations between plasma and PET beta-amyloid levels in individuals with subjective cognitive decline: the Fundació ACE Healthy Brain Initiative (FACEHBI).
de Rojas I1, Romero J2, Rodríguez-Gomez O1, Pesini P2, Sanabria A1, Pérez-Cordon A1, Abdelnour C1, Hernández I1, Rosende-Roca M1, Mauleón A1, Vargas L1, Alegret M1, Espinosa A1, Ortega G1, Gil S1, Guitart M1, Gailhajanet A1, Santos-Santos MA1, Moreno-Grau S1, Sotolongo-Grau O1, Ruiz S1, Montrreal L1, Martín E1, Pelejà E1, Lomeña F3, Campos F3, Vivas A4, Gómez-Chiari M4, Tejero MA4, Giménez J4, Pérez-Grijalba V2, Marquié GM1, Monté-Rubio G1, Valero S1, Orellana A1, Tárraga L1, Sarasa M2, Ruiz A5, Boada M1; FACEHBI study.
jpad.2018.41 F.I.: doi:org/10.14283
Plasma Aβ42/40 Ratio Detects Early Stages of Alzheimer’s Disease and Correlates with CSF and Neuroimaging Biomarkers in the AB255 Study
V. Pérez-Grijalba, J. Romero, P. Pesini, L. Sarasa, I. Monleón, I. San-José, J. Arbizu, P. Martínez-Lage, J. Munuera, A. Ruiz, L. Tárraga, M. Boada, M. Sarasa, on behalf of The AB255 Study Group
Sci Rep. 2018 Nov 5;8(1):16345 F.I.: 4,122. doi: 10.1038/s41598-018-34577-3.
Usefulness of peripapillary nerve fiber layer thickness assessed by optical coherence tomography as a biomarker for Alzheimer's disease.
Sánchez D1, Castilla-Marti M2,3, Rodríguez-Gómez O4, Valero S4,5, Piferrer A6, Martínez G7,8, Martínez J4, Serra J4, Moreno-Grau S4, Hernández-Olasagarre B4, De Rojas I4, Hernández I4, Abdelnour C4, Rosende-Roca M4, Vargas L4, Mauleón A4, Santos-Santos MA4, Alegret M4, Ortega G4, Espinosa A4, Pérez-Cordón A4, Sanabria Á4, Ciudin A9, Simó R9, Hernández C9, Villaoslada P10, Ruiz A4, Tàrraga L4, Boada M4.
Front. Aging Neurosci., 30 October 2018 F.I.: 3.582. doi: 10.3389
Exploring Genetic Associations of Alzheimer’s Disease Loci With Mild Cognitive Impairment Neurocognitive Endophenotypes.
Ana Espinosa1 , Begoña Hernández-Olasagarre1 , Sonia Moreno-Grau1 , Luca Kleineidam2,3,4, Stefanie Heilmann-Heimbach5,6 , Isabel Hernández1 , Steffen Wolfsgruber3,7 , Holger Wagner7 , Maitée Rosende-Roca1 , Ana Mauleón1 , Liliana Vargas1 , Asunción Lafuente1 , Octavio Rodríguez-Gómez1 , Carla Abdelnour1 , Silvia Gil1 , Marta Marquié1 , Miguel A. Santos-Santos1 , Ángela Sanabria1 , Gemma Ortega1 , Gemma Monté-Rubio1 , Alba Pérez1 , Marta Ibarria1 , Susana Ruiz1 , Johannes Kornhuber8 , Oliver Peters9 , Lutz Frölich10, Michael Hüll11 , Jens Wiltfang12 , Tobias Luck13 , Steffi Riedel-Heller14, Laura Montrreal1 , Pilar Cañabate1 , Mariola Moreno1 , Silvia Preckler1 , Nuria Aguilera1 , Itziar de Rojas1 , Adelina Orellana1 , Montserrat Alegret1 , Sergi Valero1 , Markus M. Nöthen5,6, Michael Wagner2,3 , Frank Jessen4,5,7, Lluis Tárraga1 , Mercè Boada1 , Alfredo Ramírez2,4 and Agustín Ruiz1 *.
Alzheimers Res Ther. 2018 Aug 23;10(1):85. F.I. 5.015. doi: 10.1186/s13195-018-0415-6.
Pharmacodynamics of atabecestat (JNJ-54861911), an oral BACE1 inhibitor in patients with early Alzheimer's disease: randomized, double-blind, placebo-controlled study.
Timmers M1,2, Streffer JR3,4,5, Russu A3, Tominaga Y6, Shimizu H6, Shiraishi A6, Tatikola K7, Smekens P3, Börjesson-Hanson A8, Andreasen N9, Matias-Guiu J10, Baquero M11, Boada M12, Tesseur I3, Tritsmans L3, Van Nueten L3, Engelborghs S4,13.
Science. 2018 Jun 22;360(6395). pii: eaap8757 F.I. 41.058. doi: 10.1126/science.aap8757
Analysis of shared heritability in common disorders of the brain.
Brainstorm Consortium, Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, Lee PH, Turley P, Grenier-Boley B, Chouraki V, Kamatani Y, Berr C, Letenneur L, Hannequin D, Amouyel P, Boland A, Deleuze JF, Duron E, Vardarajan BN, Reitz C, Goate AM, Huentelman MJ, Kamboh MI, Larson EB, Rogaeva E, St George-Hyslop P, Hakonarson H, Kukull WA, Farrer LA, Barnes LL, Beach TG, Demirci FY, Head E, Hulette CM, Jicha GA, Kauwe JSK, Kaye JA, Leverenz JB, Levey AI, Lieberman AP, Pankratz VS, Poon WW, Quinn JF, Saykin AJ, Schneider LS, Smith AG, Sonnen JA, Stern RA, Van Deerlin VM, Van Eldik LJ, Harold D, Russo G, Rubinsztein DC, Bayer A, Tsolaki M, Proitsi P, Fox NC, Hampel H, Owen MJ, Mead S, Passmore P, Morgan K, Nöthen MM, Rossor M, Lupton MK, Hoffmann P, Kornhuber J, Lawlor B, McQuillin A, Al-Chalabi A, Bis JC, Ruiz A, Boada M, Seshadri S, Beiser A, Rice K, van der Lee SJ, De Jager PL, Geschwind DH, Riemenschneider M, Riedel-Heller S, Rotter JI, Ransmayr G, Hyman BT, Cruchaga C, Alegret M, Winsvold B, Palta P, Farh KH, Cuenca-Leon E, Furlotte N, Kurth T, Ligthart L, Terwindt GM, Freilinger T, Ran C, Gordon SD, Borck G, Adams HHH, Lehtimäki T, Wedenoja J, Buring JE, Schürks M, Hrafnsdottir M, Hottenga JJ, Penninx B, Artto V, Kaunisto M, Vepsäläinen S, Martin NG, Montgomery GW, Kurki MI, Hämäläinen E, Huang H, Huang J, Sandor C, Webber C, Muller-Myhsok B, Schreiber S, Salomaa V, Loehrer E, Göbel H, Macaya A, Pozo-Rosich P, Hansen T, Werge T, Kaprio J, Metspalu A, Kubisch C, Ferrari MD, Belin AC, van den Maagdenberg AMJM, Zwart JA, Boomsma D, Eriksson N, Olesen J, Chasman DI, Nyholt DR, Avbersek A, Baum L, Berkovic S, Bradfield J, Buono R, Catarino CB, Cossette P, De Jonghe P, Depondt C, Dlugos D, Ferraro TN, French J, Hjalgrim H, Jamnadas-Khoda J, Kälviäinen R, Kunz WS, Lerche H, Leu C, Lindhout D, Lo W, Lowenstein D, McCormack M, Møller RS, Molloy A, Ng PW, Oliver K, Privitera M, Radtke R, Ruppert AK, Sander T, Schachter S, Schankin C, Scheffer I, Schoch S, Sisodiya SM, Smith P, Sperling M, Striano P, Surges R, Thomas GN, Visscher F, Whelan CD, Zara F, Heinzen EL, Marson A, Becker F, Stroink H, Zimprich F, Gasser T, Gibbs R, Heutink P, Martinez M, Morris HR, Sharma M, Ryten M, Mok KY, Pulit S, Bevan S, Holliday E, Attia J, Battey T, Boncoraglio G, Thijs V, Chen WM, Mitchell B, Rothwell P, Sharma P, Sudlow C, Vicente A, Markus H, Kourkoulis C, Pera J, Raffeld M, Silliman S, Boraska Perica V, Thornton LM, Huckins LM, William Rayner N, Lewis CM, Gratacos M, Rybakowski F, Keski-Rahkonen A, Raevuori A, Hudson JI, Reichborn-Kjennerud T, Monteleone P, Karwautz A, Mannik K, Baker JH, O'Toole JK, Trace SE, Davis OSP, Helder SG, Ehrlich S, Herpertz-Dahlmann B, Danner UN, van Elburg AA, Clementi M, Forzan M, Docampo E, Lissowska J, Hauser J, Tortorella A, Maj M, Gonidakis F, Tziouvas K, Papezova H, Yilmaz Z, Wagner G, Cohen-Woods S, Herms S, Julià A, Rabionet R, Dick DM, Ripatti S, Andreassen OA, Espeseth T, Lundervold AJ, Steen VM, Pinto D, Scherer SW, Aschauer H, Schosser A, Alfredsson L, Padyukov L, Halmi KA, Mitchell J, Strober M, Bergen AW, Kaye W, Szatkiewicz JP, Cormand B, Ramos-Quiroga JA, Sánchez-Mora C, Ribasés M, Casas M, Hervas A, Arranz MJ, Haavik J, Zayats T, Johansson S, Williams N, Dempfle A, Rothenberger A, Kuntsi J, Oades RD, Banaschewski T, Franke B, Buitelaar JK, Arias Vasquez A, Doyle AE, Reif A, Lesch KP, Freitag C, Rivero O, Palmason H, Romanos M, Langley K, Rietschel M, Witt SH, Dalsgaard S, Børglum AD, Waldman I, Wilmot B, Molly N, Bau CHD, Crosbie J, Schachar R, Loo SK, McGough JJ, Grevet EH, Medland SE, Robinson E, Weiss LA, Bacchelli E, Bailey A, Bal V, Battaglia A, Betancur C, Bolton P, Cantor R, Celestino-Soper P, Dawson G, De Rubeis S, Duque F, Green A, Klauck SM, Leboyer M, Levitt P, Maestrini E, Mane S, De-Luca DM, Parr J, Regan R, Reichenberg A, Sandin S, Vorstman J, Wassink T, Wijsman E, Cook E, Santangelo S, Delorme R, Rogé B, Magalhaes T, Arking D, Schulze TG, Thompson RC, Strohmaier J, Matthews K, Melle I, Morris D, Blackwood D, McIntosh A, Bergen SE, Schalling M, Jamain S, Maaser A, Fischer SB, Reinbold CS, Fullerton JM, Guzman-Parra J, Mayoral F, Schofield PR, Cichon S, Mühleisen TW, Degenhardt F, Schumacher J, Bauer M, Mitchell PB, Gershon ES, Rice J, Potash JB, Zandi PP, Craddock N, Ferrier IN, Alda M, Rouleau GA, Turecki G, Ophoff R, Pato C, Anjorin A, Stahl E, Leber M, Czerski PM, Cruceanu C, Jones IR, Posthuma D, Andlauer TFM, Forstner AJ, Streit F, Baune BT, Air T, Sinnamon G, Wray NR, MacIntyre DJ, Porteous D, Homuth G, Rivera M, Grove J, Middeldorp CM, Hickie I, Pergadia M, Mehta D, Smit JH, Jansen R, de Geus E, Dunn E, Li QS, Nauck M, Schoevers RA, Beekman AT, Knowles JA, Viktorin A, Arnold P, Barr CL, Bedoya-Berrio G, Bienvenu OJ, Brentani H, Burton C, Camarena B, Cappi C, Cath D, Cavallini M, Cusi D, Darrow S, Denys D, Derks EM, Dietrich A, Fernandez T, Figee M, Freimer N, Gerber G, Grados M, Greenberg E, Hanna GL, Hartmann A, Hirschtritt ME, Hoekstra PJ, Huang A, Huyser C, Illmann C, Jenike M, Kuperman S, Leventhal B, Lochner C, Lyon GJ, Macciardi F, Madruga-Garrido M, Malaty IA, Maras A, McGrath L, Miguel EC, Mir P, Nestadt G, Nicolini H, Okun MS, Pakstis A, Paschou P, Piacentini J, Pittenger C, Plessen K, Ramensky V, Ramos EM, Reus V, Richter MA, Riddle MA, Robertson MM, Roessner V, Rosário M, Samuels JF, Sandor P, Stein DJ, Tsetsos F, Van Nieuwerburgh F, Weatherall S, Wendland JR, Wolanczyk T, Worbe Y, Zai G, Goes FS, McLaughlin N, Nestadt PS, Grabe HJ, Depienne C, Konkashbaev A, Lanzagorta N, Valencia-Duarte A, Bramon E, Buccola N, Cahn W, Cairns M, Chong SA, Cohen D, Crespo-Facorro B, Crowley J, Davidson M, DeLisi L, Dinan T, Donohoe G, Drapeau E, Duan J, Haan L, Hougaard D, Karachanak-Yankova S, Khrunin A, Klovins J, Kučinskas V, Lee Chee Keong J, Limborska S, Loughland C, Lönnqvist J, Maher B, Mattheisen M, McDonald C, Murphy KC, Nenadic I, van Os J, Pantelis C, Pato M, Petryshen T, Quested D, Roussos P, Sanders AR, Schall U, Schwab SG, Sim K, So HC, Stögmann E, Subramaniam M, Toncheva D, Waddington J, Walters J, Weiser M, Cheng W, Cloninger R, Curtis D, Gejman PV, Henskens F, Mattingsdal M, Oh SY, Scott R, Webb B, Breen G, Churchhouse C, Bulik CM, Daly M, Dichgans M, Faraone SV, Guerreiro R, Holmans P, Kendler KS, Koeleman B, Mathews CA, Price A, Scharf J, Sklar P, Williams J, Wood NW, Cotsapas C, Palotie A, Smoller JW, Sullivan P, Rosand J, Corvin A, Neale BM.
J Neuropathol Exp Neurol. 2018 Jun 7 F.I.:3.490. doi: 10.1093/jnen/nly047
Systematic Screening of Ubiquitin/p62 Aggregates in Cerebellar Cortex Expands the Neuropathological Phenotype of the C9orf72 Expansion Mutation.
Ramos-Campoy O1,2, Ávila-Polo R1,3, Grau-Rivera O1,2, Antonell A2, Clarimón J4,5, Rojas-García R6, Charif S1, Santiago-Valera V1, Hernandez I7, Aguilar M8, Almenar C9, Lopez-Villegas D10, Bajo L11, Pastor P8, Van der Zee J12, Lladó A2, Sanchez-Valle R1,2, Gelpi E1,13.
Neuroimage. 2018 Jun 2. pii: S1053-8119(18)30491-9 F.I.: 5.426. doi: 10.1016/j.neuroimage.2018.05.065 doi: 10.3233/JAD-180243.
A comparison of various MRI feature types for characterizing whole brain anatomical differences using linear pattern recognition methods.
Monté-Rubio GC1, Falcón C2, Pomarol-Clotet E3, Ashburner J4.
Oncotarget. 2018 May 15;9(37):24590-24600. F.I.: 5.426. doi: 10.18632/oncotarget.25083.
Genome-wide significant risk factors on chromosome 19 and the APOE locus.
Moreno-Grau S1, Hernández I1, Heilmann-Heimbach S2,3, Ruiz S1, Rosende-Roca M1, Mauleón A1, Vargas L1, Rodríguez-Gómez O1, Alegret M1, Espinosa A1, Ortega G1, Aguilera N1, Abdelnour C1, Neuroimaging Initiative AD1,2,3,4,5,6,7,8,9, Gil S1, Maier W4,5, Sotolongo-Grau O1, Tárraga L1, Ramirez A2,4,6, López-Arrrieta J7, Antúnez C8, Serrano-Ríos M9, Boada M1, Ruiz A1.
doi: 10.1101/294629
Meta-analysis of genetic association with diagnosed Alzheimer's disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing.
Brian W. Kunkle, Benjamin Grenier-Boley, Rebecca Sims, Joshua C. Bis, Adam C. Naj, Anne Boland, Maria Vronskaya, Sven J van der Lee, Alex Amlie-Wolf, Celine Bellenguez, Aura Frizatti, Vincent Chouraki, Alzheimer's Disease Genetics Consortium (ADGC), European Alzheimer's Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), Genetic and Environmental Risk in Alzheimer's Disease Consortium (GERAD/PERADES), Helena Schmidt, Hakon Hakonarson, Ron Munger, Reinhold Schmidt, Lindsay A. Farrer, Christine Van Broeckhoven, Michael C. O'Donovan, Anita L. Destefano, Lesley Jones, Jonathan L. Haines, Jean-Francois Deleuze, Michael J. Owen, Vilmundur Gudnason, Richard P. Mayeux, Valentina Escott-Price, Bruce M. Psaty, Agustin Ruiz, Alfredo Ramirez, Li-San Wang, Cornelia M. van Duijn, Peter A. Holmans, Sudha Seshadri, Julie Williams, Philippe Amouyel, Gerard D. Schellenberg, Jean-Charles Lambert, Margaret A. Pericak-Vance. BioRxiv.
Neurobiol Aging. 2018 Feb;62:245.e1-245.e7 F.I.: 4.454. doi: 10.1016/j.neurobiolaging.2017.10.012. Epub 2017 Oct 25
Common and rare TBK1 variants in early-onset Alzheimer disease in a European cohort.
Verheijen J1, van der Zee J1, Gijselinck I1, Van den Bossche T2, Dillen L1, Heeman B1, Gómez-Tortosa E3, Lladó A4, Sanchez-Valle R4, Graff C5, Pastor P6, Pastor MA7, Benussi L8, Ghidoni R8, Binetti G9, Clarimon J10, de Mendonça A11, Gelpi E12, Tsolaki M13, Diehl-Schmid J14, Nacmias B15, Almeida MR16, Borroni B17, Matej R18, Ruiz A19, Engelborghs S20, Vandenberghe R21, De Deyn PP20, Cruts M1, Van Broeckhoven C22, Sleegers K23; BELNEU Consortium; EU EOD Consortium.
Transl Psychiatry. 2018 Apr 11;8(1):73. F.I.: 4.691. doi: 10.1038/s41398-017-0049-7.
CXCR4 involvement in neurodegenerative diseases.
Bonham LW1, Karch CM2, Fan CC3, Tan C4, Geier EG1, Wang Y5, Wen N2, Broce IJ4, Li Y4, Barkovich MJ4, Ferrari R6, Hardy J6, Momeni P7, Höglinger G8,9, Müller U10, Hess CP4, Sugrue LP4, Dillon WP4, Schellenberg GD11, Miller BL1, Andreassen OA5, Dale AM3,12, Barkovich AJ4, Yokoyama JS1, Desikan RS13; International FTD-Genomics Consortium (IFGC); International Parkinson’s Disease Genetics Consortium (IPDGC); International Genomics of Alzheimer’s Project (IGAP).
Sci Rep. 2018 May 14;8(1):7789. F.I.: 4.122. doi: 10.1038/s41598-018-21308-x.
Author Correction: Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS.
Taskesen E1,2, Mishra A1, van der Sluis S1, Ferrari R3; International FTD-Genomics Consortium, Veldink JH4, van Es MA4, Smit AB5, Posthuma D1,2, Pijnenburg Y6.
Mol Psychiatry. 2018 Apr;23(4):963-972 F.I. 11.640 doi: 10.1038/mp.2017.81. Epub 2017 May 2.
Genetic risk for schizophrenia and psychosis in Alzheimer disease.
DeMichele-Sweet MAA1, Weamer EA2, Klei L1, Vrana DT3, Hollingshead DJ4, Seltman HJ5, Sims R6, Foroud T7, Hernandez I8, Moreno-Grau S8, Tárraga L8, Boada M8, Ruiz A8, Williams J6, Mayeux R9, Lopez OL1,2, Sibille EL1,10,11, Kamboh MI12, Devlin B1, Sweet RA1,2,13.
J Alzheimers Dis. 2018 May 16. F.I.: 3.476. doi: 10.3233/JAD-180243
Increased Albumin Oxidation in Cerebrospinal Fluid and Plasma from Alzheimer's Disease Patients.
Costa M1, Horrillo R1, Ortiz AM1, Pérez A1, Mestre A1, Ruiz A2, Boada M2,3, Grancha S1.
N Engl J Med. 2018 Jan 25;378(4):321-330. F.I.: 79.258. doi: 10.1056/NEJMoa1705971.
Trial of Solanezumab for Mild Dementia Due to Alzheimer's Disease.
Honig LS, Vellas B, Woodward M, Boada M, Bullock R, Borrie M, Hager K, Andreasen N, Scarpini E, Liu-Seifert H, Case M, Dean RA, Hake A, Sundell K, Poole Hoffmann V, Carlson C, Khanna R, Mintun M, DeMattos R, Selzler KJ, Siemers E.
PLoS Med. 2018 Jan 9;15(1):e1002487. F.I.: 11.675. doi: 10.1371/journal.pmed.1002487. eCollection 2018 Jan.
Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.
Broce I, Karch CM, Wen N, Fan CC, Wang Y, Hong Tan C, Kouri N, Ross OA, Höglinger GU, Muller U, Hardy J; International FTD-Genomics Consortium, Momeni P, Hess CP, Dillon WP, Miller ZA, Bonham LW, Rabinovici GD, Rosen HJ, Schellenberg GD, Franke A, Karlsen TH, Veldink JH, Ferrari R, Yokoyama JS, Miller BL, Andreassen OA, Dale AM, Desikan RS, Sugrue LP.
J Alzheimers Dis. 2018;61(1):321-332. F.I.: 3.476. doi: 10.3233/JAD-170693.
Longitudinal Neuroimaging Analysis in Mild-Moderate Alzheimer's Disease Patients Treated with Plasma Exchange with 5% Human Albumin.
Cuberas-Borrós G, Roca I, Boada M, Tárraga L, Hernández I, Buendia M, Rubio L, Torres G, Bittini Á, Guzmán-de-Villoria JA, Pujadas F, Torres M, Núñez L, Castell J, Páez A.
Alzheimers Res Ther. 2018 Jan 29;10(1):12. F.I.: 5.015. doi: 10.1186/s13195-018-0340-8
Safety, tolerability and immunogenicity of an active anti-Aβ40 vaccine (ABvac40) in patients with Alzheimer’s disease: a randomised, double-blind, placebo-controlled, phase I trial.
Ana-María Lacosta, María Pascual-Lucas, Pedro Pesini, Diego Casabona, Virginia Pérez-Grijalba, Iván Marcos-Campos, Leticia Sarasa, Jesus Canudas, Hassnae Badi, Inmaculada Monleón, Itziar San-José, Josep Munuera, Octavio Rodríguez-Gómez, Carla Abdelnour, Asunción Lafuente, Mar Buendía, Mercè Boada, Lluis Tárraga, Agustín Ruiz, Manuel Sarasa.
Sci Rep. 2018 Feb 28;8(1):3828. F.I.: 4.122. doi: 10.1038/s41598-018-21644-y
The Spanish version of Face-Name Associative Memory Exam (S-FNAME) performance is related to amyloid burden in Subjective Cognitive Decline.
Sanabria A, Alegret M, Rodriguez-Gomez O, Valero S, Sotolongo-Grau O, Monté-Rubio G, Abdelnour C, Espinosa A, Ortega G, Perez-Cordon A, Gailhajanet A, Hernandez I, Rosende-Roca M, Vargas L, Mauleon A, Sanchez D, Martin E, Rentz DM, Lomeña F, Ruiz A, Tarraga L, Boada M; FACEHBI study group.
Neurobiol Aging. 2018 Jun;66:181.e3-181.e10. F.I.: 4.454. doi:10.1016/j.neurobiolaging.2018.02.011
Rare nonsynonymous variants in SORT1 are associated with increased risk for frontotemporaldementia.
Philtjens S, Van Mossevelde S, van der Zee J, Wauters E, Dillen L, Vandenbulcke M, Vandenberghe R, Ivanoiu A, Sieben A, Willems C7, Benussi L, Ghidoni R, Binetti G, Borroni B, Padovani A, Pastor P, Diez-Fairen M, Aguilar M, de Mendonça A, Miltenberger-Miltényi G, Hernández I, Boada M, Ruiz A, Nacmias B, Sorbi S, Almeida MR, Santana I, Clarimón J, Lleó A, Frisoni GB, Sanchez-Valle R, Lladó A, Gómez-Tortosa E, Gelpi E, Van den Broeck M, Peeters K, Cras P, De Deyn PP, Engelborghs S, Cruts M, Van Broeckhoven C; BELNEU Consortium; EU EOD Consortium25.
J Alzheimers Dis. 2018;62(3):1079-1090. F.I.: 3.476. doi: 10.3233/JAD-170866
Patient Engagement: The Fundació ACE Framework for Improving Recruitment and Retention in Alzheimer's Disease Research.
Boada M, Santos-Santos MA, Rodríguez-Gómez O, Alegret M, Cañabate P, Lafuente A, Abdelnour C, Buendía M, de Dios MJ, Morera A, Sanabria Á, Campo L, Ruiz A, Tárraga L.
J Alzheimers Dis. 2018;62(2):611-619. F.I.:3.476. doi: 10.3233/JAD-170826
The Role of Verb Fluency in the Detection of Early Cognitive Impairment in Alzheimer's Disease.
Alegret M, Peretó M, Pérez A, Valero S, Espinosa A, Ortega G, Hernández I, Mauleón A, Rosende-Roca M, Vargas L, Rodríguez-Gómez O, Abdelnour C, Berthier ML, Bak TH, Ruíz A, Tárraga L, Boada M.
Mente y cerebro, ISSN 1695-0887, Nº. 88, 2018, págs. 32-35
Los genes de la esquizofrenia que protegen del alzhéimer.
S Moreno, A Ruiz.